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Philips Buys Volcano: It's About Money, Technology, and History
Volcano and Philips logos
The acquisition of Volcano by Philips is a landmark event in the world of imaging. For years, Volcano's mantra was "angiography alone is not enough." Well now, angiography agrees and one of the largest manufacturers of cath labs will be offering IVUS, FFR and iFR modalities as part of its total imaging package. The potential spread of these technologies can only benefit patients, with better outcomes and more targeted procedures, and also save hospitals and healthcare systems money.
FDA Approves HeartFlow FFR-CT: Non-Invasive Method for Determining Coronary Ischemia
HeartFlow FFR-CT 3D Analysis
The FDA has approved HeartFlow's FFR-CT software for measuring coronary blockages non-invasively. While the accuracy of FFR-CT to correctly differentiate significant blockages from those not needing revascularization is only in the mid-80% range, the fact that a CT scan can be performed quickly, non-invasively, and with relatively low radiation doses, makes this procedure a significant contender to the extremely common nuclear stress test, and a potential game-changer in the diagnosis of coronary artery disease.
DAPT Study: Extended Treatment After Stenting Lowers Stent Thrombosis and Heart Attacks
Road map with traffic
"Longer is better." That's what Dr. Dean Kereiakis told Angioplasty.Org when characterizing the results of the long-awaited Dual Antiplatelet Therapy (DAPT) study, which were presented today at the annual American Heart Association Scientific Sessions in Chicago. Dr. Kereiakes is the co-principal investigator for this five year study of 10,000 patients, which adds to the knowledge base of whether long-term treatment with aspirin and a thienopyridine, such as Plavix, after stent implantation is beneficial to patients.
Fractional Flow Reserve: Measuring Pressures in the Marketplace
Dr. Andreas Gruentzig in cath lab
The FFR market has been a duopoly, split almost evenly between St. Jude Medical and Volcano Corporation. While these companies compete with each other, both have expressed upon occasion that the real challenge to increasing their sales and profits is not in gaining share from each other, but from expanding the field of FFR as a whole. However, some new smaller device companies are beginning to enter the marketplace. And the technology is slightly different: instead of pressure wires, these newer systems are utilizing fiber-optics.
We Live Tweeted #AIMRADIAL2014
Road map with traffic
On October 23-25, AimRADIAL 2014, the 3rd Advanced International Masterclass on the Transradial Approach, was held in Chicago: two-and-a-half days of presentations and live cases, showing the latest advances and best practices for diagnostic and interventional procedures done via the wrist. The faculty comprised the world leaders in this field. The archive of our live tweets can be found by searching the hashtag #AIMRADIAL2014. For more about the meeting, read our Editor's blog.
Will a Denial of Service DOS Attack Hit New York State Medicaid Patients? Or Perhaps Your State?
DOS Attack on Stents
What does a Denial of Service Attack have to do with stents, angioplasty and PCI? In the world of computing, a DOS attack is defined as "an attempt to make a machine or network resource unavailable to its intended users." Now it seems similarly that in New York State, cardiovascular treatments may become unavailable to some Medicaid patients: a denial of service.
FFR and iFR: Roadmapping Your Heart, With Traffic
Road map with traffic
What has become clearer in the past few years is that seeing is not believing. The angiogram may show a narrowing, but that narrowing may not be causing a reduced flow of blood to the heart, a.k.a. "ischemia." Stenting or bypassing such a "non-ischemic" narrowing may not be of much benefit to the patient, but it will add a small risk factor of stent restenosis or perhaps a surgical complication.
ZEUS: Drug-Eluting Stent Outperforms Bare Metal for Safety and Efficacy in At-Risk Patients
DES vs. BMS
The ZEUS trial of 1,606 patients showed that the use of Medtronic's Endeavor zotarolimus-eluting stent is associated with a lower risk of major cardiac events at one year compared to bare metal stents among a patient population normally excluded from treatment with drug-eluting stents.
FDA Approves Volcano's iFR® Pressure Measurement Modality for Use in Coronary Stent Guidance
Volcano's iFR system measures intracoronary pressures without need for adenosine
The FDA has granted approval to Volcano's proprietary coronary pressure measurement modality, iFR (Instant wave-Free Ratio). iFR represents a significant advance in the field of functional measurement (FM), in which the actual flow pressures inside the coronary artery can be measured and the deficit caused by a coronary blockage or lesion can be accurately assessed.
Can Near-Infrared Imaging Predict Heart Attack Risk?
Infraredx TVC Imaging System
What causes a heart attack? Is it a physical narrowing in the coronary artery, a blockage that can be seen on angiography? Or is it more likely the eruption of a lipid-rich plaque, a so-called vulnerable plaque, that may not look significant in percent stenosis during a standard catheterization? To find an answer, MedStar Heart Institute and Infraredx announced enrollment of the first patient in the Lipid-Rich Plaque (LRP) Study, which will involve 100 centers worldwide and have a target enrollment of 9,000 patients.
The Incredible Shrinking Cardiac Devices
Micra pacemaker in heart
The "world's smallest, minimally invasive cardiac pacemaker," Medtronic's Micra™ Transcatheter Pacing System, was implanted last week for the first time in the United States. This implantation comes just two-plus months after its first in-human implantation and just two weeks after its competitor St. Jude Medical announced the "first in U.S." implantation of its own miniaturized device, the Nanostim™ leadless pacemaker.
DUTCH PEERS: Resolute Integrity vs. Promus Element 3rd Generation Stents
Medtronic's Resolute Integrity and Boston Scientific's Promus Element
Are 3rd generation drug-eluting stents interchangeable? And what exactly is a "third generation" drug-eluting stent anyway? These were questions addressed by the DUTCH PEERS randomized clinical trial. The results showed that the Resolute Integrity was non-inferior to the Promus Element. There was, however, one parameter in which the two stents were not the same: longitudinal stent deformation.
50 Years Ago, Dr. Charles Dotter Invented Angioplasty
Charles Dotter, MD
It was 50 years ago that Dr. Charles T. Dotter, a radiologist in Portland, Oregon, performed the first angioplasty. But it wasn't in the heart; it was in the leg. An 82-year-old woman was scheduled for amputation of a gangrenous foot, but Dotter had a theory that he could open her blocked leg artery without surgery, with a catheter, and save her foot. He was right....
The Great Angioplasty Non-Debate
Questions about stents
A prominent physician, Dr. Nortin Hadler, has now posted two op-ed pieces claiming that angioplasty and stents are no better than clot-busters for the treatment of heart attacks. We disagree strongly and state our case, citing the significant clinical data that shows angioplasty to be the "gold standard."
Wrist Angioplasty Sees Unprecedented Growth in U.S.
Radial growth in the U.S.
In the current issue of Circulation, a landmark analysis of almost 3 million coronary interventions performed in the U.S. from 2007 to 2012 concludes that utilization of the transradial approach, in which balloons and stents are delivered to the heart via the radial artery in the wrist instead of the femoral artery in the groin, has increased 13-fold in the past five years.
Interventional Cardiologist Dr. Sanjay Patel
"The Whole Story is About Increasing Patient Happiness."
Interview with Dr. Ferdinand Kiemeneij
In this two-part 20th anniversary interview, the "father of transradial intervention, " talks about the history and future of TRI.
Interventional Cardiologist Dr.Ron Caputo
"Transradial Has Gone From a Physician-Centered to an Institutional Concern."
Interview with Dr. Ron Caputo
The landscape of transradial has changed in the past 5 years from introductory "evangelical" didactic lectures to mentorship and adoption by hospitals for economic benefit and improved patient care..

Angioplasty News

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Philips Buys Volcano: It's About Money, Technology & History (Dec 19)
Philips to Acquire Volcano for $1.2 Billion (Dec 17)
Volcano: 1,000 iFR Systems in Use Worldwide (Dec 16)
Excellent Long-Term Outcomes for EVAR with Medtronic's Endurant AAA Stent Graft (Dec 9)
From Bench to Bedside to Bench Revisited: Supreme Court Justice Ginsburg Back in Action (Dec 1)
Supreme Court Justice Ginsburg Released from Hospital 1 Day After Receiving Stent (Nov 27)
Medtronic Acquisition of Covidien Gets FTC Clearance (Nov 26)
FDA Approves HeartFlow FFR-CT: Non-Invasive Method for Determining Coronary Ischemia (Nov 26)
1 Year Data from EVOLVE II Trial Shows Safety & Efficacy for Boston Scientific's SYNERGY Bioabsorbable Polymer Stent (Nov 21)
Encouraging Results for Lombard's Aorfix AAA Stent Graft (Nov 20)
The Beginnings of EVAR Endovascular AAAA Repair (Nov 18)
DAPT Study: Extended Treatment After Stenting Lowers Stent Thrombosis & Heart Attacks (Nov 16)
Plavix and Aspirin After Stent: 8 Years Later – Is Longer Better? (Nov 16)
New AAA Stent Graft Approval for Medtronic (Nov 14)
Medtronic Sponsors American Diabetes Association Educational Campaign for 2nd Year (Nov 14)
Vascular Surgery and the Battlefield: Honoring Our Veterans (Nov 11)
Fractional Flow Reserve: Measuring Pressures in the Marketplace (Nov 6)
Crazy Charlie's Amazing Idea: Angioplasty at 50 (Nov 5)
5-Year Data for Zilver PTX Drug-Eluting Stent for Leg Arteries Show Continued Efficacy (Nov 4)
IN.PACT Drug-Coated Balloon Shows Safety & Efficacy for Peripheral Angioplasty in Diabetics (Nov 4)
VIVA 2014 Starts in Las Vegas - Looking Back at the 1st EVAR (Nov 3)
Medtronic's New Onyx Drug-Eluting Stent Gains CE Mark (Nov 3)
Opsens Files To Become a New Player in FFR Market (Oct 20)
Boston Sci Begins Study of DES in Women and Minorities (Oct 20)
FFR and Ebola: Thresholds and Decision-Making (Oct 16)
FDA OK to Medtronic's MRI-Safe Pacing Lead (Oct 14)
Positive 30-Day Results in CoreValve Direct Aortic Study (Oct 13)
FDA Approves Lutonix: 1st Drug-Coated Balloon for PAD (Oct 12)
ACIST Showcases Hi-Definition IVUS System (Oct 8)
Will a Denial of Service DOS Attack Hit NYS Medicaid Patients? (Oct 5)
FFR and iFR: Roadmapping Your Heart, With Traffic (Oct 3)
Japanese Approval for Infraredx NIR/IVUS Imaging System (Sep 30)
Engaged Sends a Letter to Volcano Corporation, and Volcano Replies (updated Sept 30)
Medtronic DCB Shows Strong Clinical & Economic Benefit (Sep 16)
FDA OKs Medtronic's Euphora Non-Compliant Balloon (Sep 11)
Medtronic Begins U.S. Trial of Recapturable CoreValve (Sep 10)
Abbott's MitraClip® Gets Expanded Medicare Coverage (Aug 12)
Medtronic Enters the FFR/ IVUS Field With ACIST Co-Promotion (Aug 4)
Boston Scientific Gets FDA Approval for REBEL Bare Metal Stent (Jul 26)
Boston Scientific Launches POLARIS Imaging System (Jul 22)
Boston Scientific Gets CE Mark For 25mm Lotus Valve (Jul 14)
NEJM: Medtronic ICMs Superior to Standard Care in Detecting AF in Stroke Patients (Jun 25)
Edwards Sapien XT Gains FDA Approval (Jun 16)
Medtronic CoreValve Gets Expanded FDA Approval for Patients at High Risk for Surgery (Jun 12)
Volcano Corp Announces Agreement To Acquire AtheroMed (May 27)
SCAI and CRF Training Programs in Transradial PCI (May 13)
Abbott's MitraClip Approved in Canada (May 4)
Limited Market Release of Volcano's SyncVision™ Technology (Apr 25)
MARS Across the Hudson: Mid- Atlantic Radial Symposium (Apr 17)
Valve Wars, Part III: Edwards Gets Injunction Against Medtronic (Apr 14)
FDA Approves Start of Trial for Cobra PzF™ Stent (Apr 11)
Abbott's Absorb Bioresorbable Scaffold Completes Enrollment in 3 Pivotal Clinical Trials (Apr 10)
ZEUS: Zotarolimus Stent Outperforms BMS for Safety and Efficacy in At-Risk Patients (Mar 31)
4 Yr. Data: CoreValve Demonstrates Long-Term Durability (Mar 31)
Robot Stent Placement in the Cath Lab (Mar 30)
Global SYMPLICITY Registry Shows Strong Safety Profile of Renal Denervation System (Mar 30)
CoreValve Superior to Open Surgery at 1 Year in U.S. Pivotal Trial; FDA Waives Advisory Panel (Mar 29)
LOTUS™ Valve Demonstrates Sustained Safety and Efficacy Outcomes at 3 Months (Mar 29)
Medtronic Releases Results of SYMPLICITY HTN-3 (Mar 29)
FDA OKs Volcano's iFR for Use in Coronary Stent Guidance (Mar 19)
Boston Sci Gets CE Mark for REBEL: a "New" Bare Metal Stent (Mar 17)
Medtronic Seeking Long-Distance Runners (Mar 10)
Can Near-Infrared Imaging Predict Heart Attack Risk? (Feb 27)
The Incredible Shrinking Cardiac Devices (Feb 24)
Cordis Gets CE Mark for RENLANE Renal Denervation System (Feb 24)
Angioplasty Arrives in the Outback: First Stent Placed in NT (Feb 20)
Medtronic Announces Global Launch of Miniature Cardiac Monitor, Reveal LINQ™ ICM (Feb 19)
Medtronic Launches New Peripheral BTK Catheter in Europe (Feb 13)
DUTCH PEERS: Are Resolute Integrity & Promus Element Stents Equivalent? (Feb 11)
Capsule-Sized Leadless Pacemakers May Lead the Way in Heart Rhythm Management (Feb 9)
FDA Approves Medtronic's Valiant Captivia Stent Graft for Aortic Dissections (Jan 28)
VIDEO: St. Luke's Mid America Heart Institute Awarded $3.4M Grant by Boston Sci for CTO Study (Jan 27)
FDA Approves Medtronic's CoreValve; Device Available Immediately in U.S. (Jan 17)
VIDEO: 50 Years Ago Today Charles Dotter Invented Angioplasty (Jan 16)
Another Viewpoint on Renal Denervation and SYMPLICITY HTN-3 from Dr. Darrel Francis (Jan 13)
Medtronic's U.S. Renal Denervation Trial Fails Efficacy Endpoint (Jan 9)
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Patients Are Talking About...
  • I had radial angiography 2 days ago...it was a fascinating experience and was able to watch part of the procedure. I feel fantastic, have no "heart ache" or any problems with my arm.
  • I can't afford my post-stenting meds, where can I find help paying for Plavix or Effient?
  • I'm 64. After 4 stents and 2 heart attacks since Dec. 2008, I'm as physically active or more so than ever. I plan to hit 4,000 miles on my bike this year. I've hiked/climbed at 13,000 feet.
Patients Are Reading About...
Plavix and Stent
Patient Alert!: How to Get the Best Price on New Generic Plavix
Our survey found prices from 35¢ to $6 per pill. Read on for more resources to help you get the most affordable antiplatelet drugs, plus a look at the role of online patient communities.
5 Crucial Questions To Ask Your Doctor About New Heart Disease Treatments
Make sure you are benefiting from the most up-to-date research, and have access to the treatments that best fit your needs and preferences.
   Doctor and Patient
Radial Hospital Locator
A list of physicians and hospitals offering the transradial (wrist) approach to angiograms, angioplasty and stent procedures.
  Transradial Hospital
Read patient stories and Learn about medications after stenting, symptoms and complications, care giving, taking charge of your health, communicating with your cardiologist and much more in our Patient Center.
Angioplasty Inventor, Dr. Andreas Gruentzig
see video clip:
" The 1st Angioplasty"
ANGIOPLASTY AT 35: 2012 marked the 35th anniversary of coronary angioplasty. In 1977 in Zurich, Switzerland, a young physician named Andreas Gruentzig inserted a catheter into a patient's coronary artery and inflated a tiny balloon, successfully opening a blockage and restoring blood flow to a human heart.
Today over two million coronary angioplasties are performed worldwide each year and angioplasty has become the gold standard for emergency heart attack treament.
(View videos, interviews, and photos in our Angioplasty History Center, or order our DVD, "PTCA: A History.") Angioplasty History DVD
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